Prognostic value of microRNA-21/ Ki-67 in non-Hodgkin's lymphoma: NCI experience
نویسندگان
چکیده
منابع مشابه
Non-Hodgkins Lymphoma presenting as Garcin’s Syndrome
An 80 year old man presented with a twelve month history of progressive multiple unilateral cranial nerve palsies. A gadolinium enhanced MRI scan of his head and neck was performed. This showed an extra-axial enhancing lesion, which enveloped the hemi-mandible at the level of the left inferior alveolar nerve, and a dumbbell shaped lesion within the cerebellopontine angle. An incisional biopsy w...
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BACKGROUND A high Ki-67 proliferation index (PI) in neoplastic cells is associated with poor survival in mantle cell lymphoma (MCL). We aimed to determine the cut-off values for the Ki-67 PI as a prognostic factor in MCL according to bone marrow findings. METHODS Immunohistochemical (IHC) staining for Ki-67 was performed on formalin-fixed paraffin-embedded biopsy tissues from 56 patients with...
متن کاملPrognostic Value of Ki-67 Labeling Index and Postoperative Radiotherapy in WHO Grade II Meningioma.
OBJECTIVE This study was performed to determine the clinical significance of the Ki-67 labeling index (LI) for local control (LC) in patients with World Health Organization (WHO) grade II meningioma. We also tried to discern the effect of postoperative radiotherapy (PORT) on LC depending upon the Ki-67 LI value. MATERIALS AND METHODS The medical records and values of Ki-67 LIs were retrospect...
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In 1983, Gerdes, Schwab, Lemke and Stein reported upon a new monoclonal antibody which was generated by immunizing mice with nuclei of the Hodgkin lymphoma cell line L428. This antibody was found to label nuclei of proliferating cells including tumor cells. In their report the authors therefore concluded that “Ki-67 (a name derived from the city of Kiel where the authors worked, and the number ...
متن کاملPrognostic value of Ki-67 compared to S-phase fraction in axillary node-negative breast cancer.
The primary purpose of this study was to evaluate the prognostic significance of Ki-67, a cell proliferation-associated antigen, in a large group (n = 674) of axillary node-negative breast cancer cases with long-term follow-up and to correlate Ki-67 antigen expression with S-phase fraction. Ki-67 immunostaining was assessed both semiquantitatively and quantitatively. The statistical analysis fo...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2019
ISSN: 0923-7534
DOI: 10.1093/annonc/mdz251.009